Pipobromanum [Inn-Latin]
Brand names,
Pipobromanum [Inn-Latin]
Analogs
Pipobromanum [Inn-Latin]
Brand Names Mixture
Pipobromanum [Inn-Latin]
Chemical_Formula
C10H16Br2N2O2
Pipobromanum [Inn-Latin]
RX_link
No information avaliable
Pipobromanum [Inn-Latin]
fda sheet
Pipobromanum [Inn-Latin]
msds (material safety sheet)
Pipobromanum [Inn-Latin]
Synthesis Reference
No information avaliable
Pipobromanum [Inn-Latin]
Molecular Weight
356.054 g/mol
Pipobromanum [Inn-Latin]
Melting Point
> 300 oC
Pipobromanum [Inn-Latin]
H2O Solubility
2490 mg/L
Pipobromanum [Inn-Latin]
State
Solid
Pipobromanum [Inn-Latin]
LogP
0.256
Pipobromanum [Inn-Latin]
Dosage Forms
Tablet (25 mg)
Pipobromanum [Inn-Latin]
Indication
For the treatment of polycythaemia vera and refractory chronic myeloid leukaemia.
Pipobromanum [Inn-Latin]
Pharmacology
Pipobroman is an antineoplastic agent. Specifically it is a piperazine derivative with a chemical structure close to that of many DNA alkylating agents. Pipobroman has well documented clinical activity against polycythemia vera and essential thrombocythemia.
Pipobromanum [Inn-Latin]
Absorption
Well absorbed from the GI tract.
Pipobromanum [Inn-Latin]
side effects and Toxicity
Symptoms of overdose include hematologic toxicity, especially with chronic overdosage.
Pipobromanum [Inn-Latin]
Patient Information
No information avaliable
Pipobromanum [Inn-Latin]
Organisms Affected
Humans and other mammals